Atropinum compositum
Injection solution
Atropinum compositum S
Suppositories
Composition:
Injection solution: 2.2 ml cont.: Bryonia Ø 0.44 ml; Cuprum aceticum D 2, Berberis Ø, Pareira brava Ø, Colocynthis Ø, Veratrum Ø, Arsenicum album D 4 0.22 µl each; Baptisia Ø, Chelidonium Ø 66 nl each; Cantharis D 5, Medorrhinum-Nosode D 10 22 nl each; Thuja Ø, Clematis Ø 6.6 nl each; Acidum benzoicum e resina D 2 2.2 nl; Argentum nitricum D 1 0.22 nl; Atropinum sulfuricum D 4 2.198 ml.
Suppositories (S): 1 suppository cont.: Bryonia Ø 0.22 mg; Cuprum aceticum D 2, Berberis Ø, Pareira brava Ø, Colocynthis Ø, Veratrum Ø, Acidum arsenicosum D 4 0.11 mg each; Baptisia Ø, Chelidonium Ø 0.033 mg each; Cantharis D 5, Medorrhinum-Nosode D 10 0.011 mg each; Thuja Ø, Clematis Ø 3.3 µg each; Acidum benzoicum e resina D 2 1.1 µg; Argentum nitricum D 1 0.11 µg; Atropinum sulfuricum D 3 0.011 g.
Indications:
Biliary colic, renal colic, intestinal colic in children, convulsive coughs, whooping cough, dysmenorrhoea.
Contraindications:
Injection solution: Infants and small children. Glaucoma and atonic disorders in voiding from the bladder (e.g., with prostatic adenoma); mechanical narrowing (stenosis) in the region of the gastrointestinal tract; megacolon; tachyarrythmia.
Suppositories: Narrow angle glaucoma; prostatic adenoma with residual urine; mechanical narrowing (stenosis) in the region of the gastrointestinal tract; megacolon; tachyarrythmia.
Side effects:
Injection solution: In rare cases, children may experience excessive dilation of the pupils of the eyes (mydriasis) and dryness of the mouth.
Suppositories: None known.
Interactions with other medication: None known.
Dosage:
Injection solution: In general, 1 ampoule i.m., s.c., i.d., if necessary slowly i.v., 3-1 times weekly. In cases of pain and colic, the single dose can be increased, according to the tolerance of the individual, to 3 ampoules maximum. The daily maximum dosage for adults is 6 ampoules, and for children 3 ampoules.
Suppositories: Unless otherwise prescribed, 1 suppository 2-3 times daily; in the case of painful conditions and colic, insert 1-2 suppositories into the anus every half hour, repeating the dosage until the condition is alleviated. Maximum daily dosage for adults: 12 suppositories; for children of 6-12 years: 5 suppositories; for children of 3-5 years: 3 suppositories; for infants of 3 months to 2 years: 2 doses of one suppository each.
Package sizes:
Injection solution: Packs containing 5, 10, 50 and 100 ampoules of 2.2 ml.
Suppositories: Packs containing 12, 60 and 120 suppositories of 2.0 g.
Pharmacological and clinical notes
Bryonia (bryony)
Inflammation of all serous membranes; violent stabbing pains.
Cuprum aceticum (copper (II) acetate)
Cramp of the plain and striped musculature.
Berberis (barberry)
Renal and vesical disorders, nephrolithiasis gallstones, arthritic and rheumatic diseases.
Pareira brava (pareira)
Inflammatory disorders of the urinary tract, such as cystitis, cystopyelitis, prostatic adenoma (1st stage).
Colocynthis (bitter-apple)
Sudden stabbing pains, independent of movement and rest, colics (causing the patient to writhe).
Veratrum (white hellebore)
Tendency to collapse and conditions of collapse with cyanotic or pallid and cool skin as well as cold sweat.
Arsenicum album (white arsenic)
Burning pains, restlessness, hopelessness.
Baptisia (wild indigo)
Extremely painful conditions of the musculature, septic states.
Chelidonium (celandine)
Biliary colic, pains below the right shoulder blade.
Cantharis (Spanish fly)
Burning pains with severe strangury, cystitis.
Medorrhinum-Nosode (medorrhinum nosode)
Constitutional remedy for renal and vesical disorders.
Thuja (Arbor vitae)
Constitutional remedy with particular action on the skin and the urogenital organs.
Clematis (clematis)
Vesicular, highly irritating eczema, urethral stricture, prostatitis.
Acidum benzoicum (benzoic acid)
Urid acid diathesis, gout, pains which change their position suddenly.
Argentum nitricum (silver nitrate)
Splinter pains, agoraphobia, headache, pains which increase and gradually decrease.
Atropinum sulfuricum (atropine sulphate)
Biliary and renal colic, relieves cramp, antispasmodic action.
The pharmacological effect is based on the synergism of various individual homoeopathic remedies which exert both a symptomatlc and constitutional action on lithiasis, on the general homotoxin level and on the system.
Berberis, Pareira brava, Baptisia, Arsenicum album, Argentum nitricum and Cantharis act on the renal system; Chelidonium and Atropinum sulfuricum act particularly on the biliary system, and Veratrum (e.g. in conditions of collapse with cold sweat), Cuprum aceticum (effective in relieving cramp) and especially Atropinum sulfuricum are effective for colic. In addition, constitutional effects are brought about by Medorrhinum-Nosode, Thuja, Arsenicum album. Accompanying conditions of catarrh and inflammatory symptoms of the mucosa are influenced favourably by Argentum nitricum, Arsenicum album and Bryonia. Alternating remedies frequently required are Mucosa compositum (biliary and renal colic), Momordica compositum and Leptandra compositum (chronic and acute disorders of the pancreas), Hepar compositum, Hepeel, Injeel-Chol, Chelidonium-Homaccord (cholangitis and cholecystitis), Nux vomica-Homaccord and Veratrum-Homaccord (intestinal colic).
Especially certain effects result in biliary colic when, in addition, Atropinum compositum, preferably in the form of a mixed injection, is administered with Mucosa compositum or with Hepar compositum, and, in fact, in the form of wheals along the right costal arch. A part of the mixed injection should also be given segmentally at the vertebral column as wheals near the right shoulder blade.
If, in renal colic, no rapid action occurs, injections of Berberis-Homaccord and Cantharis-Injeel are indicated, as well as Reneel (1 tablet every 15 minutes).
The dosage is adjusted according to the illness, the clinical appearance and the stage of the disease.